This week we're back asking and answering more commonly asked questions on our Quick Guides series. One of these questions is how to dilute ingredients down to a specific concentration. Read on to find out how.
Why Should I Learn to Make Dilutions?
Certain ingredients like acids come in standard concentrations, such as 70% glycolic acid, 80% lactic acid, and 1% hyaluronic acid. But you may want to have a different concentration in your product. For example, you may want to have a total of 10% AHAs in your peel. So how on earth do you go from a 70% concentration of glycolic acid down to 10%?!
This is where dilutions come in.
Dilutions, concentrations and percentages are commonly found in chemistry, but fortunately you don't need to be a chemist to work with them! There is a simple equation that makes use of grade school math and a calculator that you can use to find out the dilutions required in order to achieve specific concentrations of actives in your products.
The equation is:
C1V1 = C2V2 - where C is the concentration (%) and V is the volume (mils, or in our case we measure by weight not volume so it will be grams).
If you know any three of the values you can solve for the fourth!
Let's do an example:
Say we have some glycolic acid 70%, but we want to make a peel that contains a final concentration of 10% glycolic acid. How much glycolic acid do we need to use, and how much do we need to dilute it by?
- We know C1, the starting concentration: glycolic acid is 70%.
- We also know C2, our end concentration, because we have decided we want it to be 10%.
- I like working in amounts of 100g (or 100ml), because 100 is a nice round number to play with, and it is a 1:1 conversion from percentages. So here, 100g will be our V2. If you want a different amount you can simply change it to whatever you want.
So we will be solving for V1. Rearrange the equation to look like this:
V1 = C2V2/C1
Put your % amounts into decimal form for ease of calculation, eg. 10% = 0.1
V1 = (0.1 x 100)/0.7
V1 = 14.29g
- So you will dilute 14.29g of glycolic acid 70% with 85.71g (100g - 14.29g) of water or other ingredients to end up with 100g solution of 10% glycolic acid.
The C1V1 = C2V2 equation can be used for any concentration that you want to convert into a different concentration.
12 comments
Hi Sarah, don’t worry about molecular weight. If your glycolic acid is 99% strength then that is all that matters. You can simply input the 99 into the equation.
What if I have I have the molecular weight of 90.08g of 99% glycolic acid? Would i substitute that number for 100g in the equation? To make a 70% glycolic peel or dilution ?
Hi Emma, that’s still pretty strong, but yes you can make any concentration you like. Just be careful when using it on the skin
Hi there, can we make a 60% solution from 70% glycolic acid concentration?
Hi Lauren, that’s correct!